METHODS AND COMPOSITIONS FOR TARGETING FENESTRATED VASCULATURE

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Abstract

Targeting of a fenestrated vasculature at a body site by micro or nanoparticles can be increased by using particles that have a radius substantially equal to a critical radius of a normal vasculature at the body site. The particles can be used for treating or monitoring a physiological condition responsible for the fenestrated vasculature. A method of improving an ability of micro or nanoparticles to target fenestrated blood vessels in a body site by selecting particles from a population of the micro or nanoparticles, where the selected particles have a radius that permits enhanced delivery into the fenestrated blood vessels.

Classe Tecnologica

A - Human Necessities

Patent Office

United States Patent and Trademark Office

Numero Deposito

US2010074958

Anno Deposito

2006

Anno Concessione

2010

Inventori Pugliesi

  • Decuzzi Paolo

Tutti gli inventori

  • Paolo Decuzzi
  • Mauro Ferrari

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • Board Of Regents Of The University Of Texas System
  • The Ohio State University Research Foundation