HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

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Abstract

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Classe Tecnologica

C - Chemistry and Metallurgy

Patent Office

European Patent Office

Numero Deposito

EP 3126332

Anno Deposito

2015

Anno Concessione

2017

Inventori Pugliesi

  • Purgatorio Rosa

Tutti gli inventori

  • Arancio Ottavio
  • Deng Shixian
  • Landry Donald W
  • Fiorito Jole
  • Purgatorio Rosa
  • Amengual Jennifer Effie
  • O'conner Owen Anthony

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • The Trustees Of Columbia University In The City Of New York